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- Structural basis of actin filament assembly and aging - Nature
The structures show that actin polymerization induces the relocation of water molecules in the nucleotide-binding pocket, activating one of them for the nucleophilic attack of ATP
- Actin chromobody imaging reveals sub-organellar actin dynamics
Here we employ fluorescent protein-tagged actin nanobodies, aka “actin chromobodies” (AC) 1, 2, fused to organelle membrane targeting sequences to facilitate live cell imaging of sub-organellar actin dynamics with high spatiotemporal resolution
- Simulated actin reorganization mediated by motor proteins
Using a realistic stochastic model that simulates actin filament and motor protein dynamics and interactions, we systematically vary motor protein kinetics and investigate their effect on actin filament organization
- Actin: Static and Dynamic Studies | SpringerLink
The actin cytoskeleton is a highly dynamic network in plant cells, which is precisely regulated by numerous actin-binding proteins Hence, characterizing the biochemical activities of actin-binding proteins is of great importance Here we describe methods for
- Dr Tim Hawkins - Durham University
Actin–membrane interactions mediated by NETWORKED2 in Arabidopsis pollen tubes through associations with Pollen Receptor-Like Kinase 4 and 5 New Phytologist, 216 (4), 1170-1180 https: doi org 10 1111 nph 14745
- Targeting CaMKK2 Inhibits Actin Cytoskeletal Assembly to Suppress . . .
CaMKK2 regulates actin cytoskeletal dynamics to promote tumor invasiveness and can be inhibited to suppress metastasis of breast and ovarian cancer, indicating CaMKK2 inhibition as a therapeutic strategy to arrest disease progression
- A NET4-RabG3 couple mediate the link between actin and the . . . - bioRxiv
Taken together, we conclude that the actin cytoskeletal remodelling during stomatal closure depends on a molecular link between actin filaments and the tonoplast, which is mediated by the NET4-RABG3b interaction
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