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- Treatment for HER2-Negative Advanced Breast Cancer - WebMD
If your breast cancer is HER2-negative and advanced, what are your treatment options? Learn how hormonal therapies, chemotherapy, targeted therapies, and immunotherapy may help you
- HER2-Negative Breast Cancer: Meaning Treatment
HER2-negative breast cancer involves having cancerous cells in your breast that don’t contain high levels of the protein human epidermal growth factor 2 (HER2) With most breast cancers, hormones and or the HER2 protein fuel cancer growth For example, with HER2-positive breast cancer, excess HER2 leads to cancerous tumors
- Treatment of Stage IV (Metastatic) Breast Cancer
Women with stage IV breast cancer are most often treated with hormone therapy, chemotherapy, targeted therapy, immunotherapy, or some combination of these Surgery or radiation might be used to help prevent or treat symptoms
- Treatment for hormone receptor-positive, HER2-negative advanced breast . . .
ET alone or in combination with targeted for metastatic hormone receptor-positive, HER2-negative breast cancer is presented here The treatment of HER2-positive disease is discussed elsewhere, as is chemotherapy for ET-resistant, metastatic hormone receptor-positive breast cancer
- Updates to the Management of HR-Positive, HER2-Negative Breast Cancer . . .
Metastatic hormone receptor–positive, HER2-negative breast cancer treatment is increasingly individualized as more of the tumor landscape is described and targeted therapies are developed CDK4 6 inhibitors have demonstrated consistency in prolonging progression-free survival across several clinical trials in advanced disease Research in endocrine therapy highlighted the noninferiority of
- ASCO 2025 Metastatic Breast Cancer Updates | Breast Cancer Research . . .
This is the first study to evaluate the efficacy and safety of using sacituzumab govitecan (SG Trodelvy®, an antibody-drug conjugate) plus pembrolizumab (Ketruda®, a checkpoint inhibitor) as a first-line treatment for patients with previously untreated advanced triple-negative breast cancer (TNBC) that is PD-L1–positive
- Treatment of Breast Cancer by Stage - NCI
The stage of breast cancer is an important factor in determining which type of treatment may work best for you Learn more about treatment options for breast cancer by stage
- Stage 4 (IV) Breast Cancer: Survival Rates, Treatment Prognosis
Approximately 70% of Stage 4 breast cancer patients have HR+, HER2-negative metastatic disease, and are candidates to receive a new classification of drugs called CDK4 6 inhibitors
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