|
- Dr. Jarred Youngers YouTube talks: tests to get, glial cell . . .
Recently I came across Dr Jarred Younger's YouTube talks on ME CFS generally and his research in particular (For those not familiar with him, Dr Younger is a leading researcher in ME CFS and related conditions such as fibromyalgia He is a professor at the University of Alabama - Birmingham )
- Microglial activation states drive glucose uptake and FDG-PET . . .
12 patients with Alzheimer’s disease and 21 patients with four-repeat tauopathies also exhibited a positive association between glucose uptake and microglial activity as determined by 18F-GE-180 18-kDa translocator protein PET (TSPO-PET) in preserved brain regions, indicating that the cerebral glucose uptake in humans is also strongly
- Research teams find widespread neuroinflammation in the brains of . . .
TSPO levels in a structure called the cingulate gyrus -- an area associated with emotional processing where neuroinflammation has been reported in patients with chronic fatigue syndrome -- corresponded with patients reported levels of fatigue
- A systematic review of neurological impairments in myalgic . . .
Using positron emission tomography, we recently demonstrated elevated brain levels of the 18 kDa translocator protein (TSPO), a glial activation marker, in chronic low back pain (cLBP) patients, compared to healthy controls (HCs)
- Second study might confirm neuroinflammation in ME subcortical brain
I don't know if it was your explanation or my brain is working better today, but your two posts above re inflammation and TSPO (this one and this one) were amazingly easy to follow and comprehend Thanks, that's a true compliment
- Neuroinflammation and Cytokines in Myalgic Encephalomyelitis Chronic . . .
For example, a PET study of TSPO binding may find differences between patients and controls when using a cerebellum reference, and this holds some value for the “this is a real condition” argument But because of the difficulty in interpretation, such a study is less valuable for discerning actual pathophysiology
|
|
|