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  • Benzodiazepines and Z-Drugs: An Updated Review of Major Adverse . . .
    Abstract Various adverse events resulting from, or associated with, benzodiazepine and or Z-drug use have been extensively reported on and discussed in great detail within the biomedical literature It is widely accepted that motor vehicle accidents and falls leading to fractures in older adults are major adverse events that have been shown to occur more frequently in users of sedative
  • Intravenous (IV) Sedation Uses and Benefits - Verywell Health
    Learn about intravenous sedation (IV sedation) or monitored anesthesia care (MAC), when it is used, the benefits, and the risks
  • People with insomnia: experiences with sedative hypnotics and risk . . .
    Sedative hypnotics form an important part of managing insomnia and are recommended for short‐term use It is standard practice for clinicians to inform the patient to use medications only ‘when required’, but the use of these medications is often
  • Pharmacology of commonly used analgesics and sedatives in the ICU . . .
    The ideal sedative or analgesic agent should have a rapid onset of activity, a rapid recovery after drug discontinuation, a predictable dose response, a lack of drug accumulation,and no toxicity Unfortunately, none of the earlier analgesics, the benzodiazepines,or propofol share all of these charac …
  • The Impact of Sedative Choice on Intracranial and Systemic . . . - PubMed
    Although sedative use is near-ubiquitous in the acute management of moderate to severe traumatic brain injury (m-sTBI), the evidence base for these agents is undefined This review summarizes the evidence for analgosedative agent use in the intensive care unit management of m-sTBI Clinical studies of sedative and analgosedative agents currently utilized in adult m-sTBI management (propofol
  • Sedative load of medications prescribed for older people with dementia . . .
    The objective of this study was to determine the sedative load and use of sedative and psychotropic medications among older people with dementia living in (residential) care homes Medication data were collected at baseline and at two further
  • Ch. 13. 1: Sedative-Hypnotics and CNS Depressants – Introduction to . . .
    Ch 13 1: Sedative-Hypnotics and CNS Depressants What are Sedative-Hypnotics and CNS Depressants? Sedative-hypnotic, tranquilizer, and central nervous system (CNS) depressant drugs slow down brain activity, calming brain excitability This effect is typically mediated through enhancing the activity of GABA neurotransmitter activity (Begun, 2020)—GABA (gamma-aminobutyric acid) is one of the
  • Hypnotic Sedative Agent - an overview | ScienceDirect Topics
    Sedative-Hypnotics Despite the early use of benzodiazepines for treating RLS and PLMD, the sedative-hypnotic agents do not have reliable effectiveness in eliminating RLS sensations or eliminating PLMS They are best reserved for mild cases with primary sleep disruptions or as adjunctive therapy




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