Clinical efficacy and mechanisms of biologics for chronic . . . We review CRSwNP clinical trial and real-world data on the effectiveness and safety of biologics, discuss their therapeutic mechanisms, assess outcomes of biologic therapy versus endoscopic sinus surgery, and discuss therapies in development and future directions (J Allergy Clin Immunol 2025;155:1401-10 )
Current diagnostic and therapeutic management of chronic . . . This article aims to describe the current diagnostic and therapeutic practices for managing chronic rhinosinusitis with nasal polyps (CRSwNP) among Austrian ENT specialists A cross-sectional
Efficacy and Safety of Biologics for Chronic Rhinosinusitis . . . Dupilumab, omalizumab, mepolizumab, and benralizumab have demonstrated good efficacy and safety in the treatment of severe uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP) in phase 3 randomised controlled trials (RCTs) With recent regulatory approvals, there has been a surge in real-w …
Twice-Yearly Biologic Effective Against Nasal Polyps Enrollment required a nasal polyp score of 5-8 and either 3 consecutive days of systemic steroid treatment in the past 2 years or any previous surgery for nasal polyps