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- Lutein, zeaxanthin reaffirmed over beta-carotene in AREDS2
A decade’s worth of data shows substituting lutein-zeaxanthin for beta-carotene remains beneficial for patients with age-related macular degeneration (AMD), averting an added risk for lung disease in specific populations
- Understanding AREDS2 Side Effects: What the Experts Don’t Always Share
This led to the replacement of beta-carotene with the macular carotenoids lutein and zeaxanthin—nutrients known for their powerful antioxidant properties and their role in supporting macular health The updated AREDS2 formula now includes lutein, zeaxanthin, vitamin C, vitamin E, zinc, and copper
- A 10-Year Follow-up Affirms AREDS2 with Lutein Still Effective, Safe
In AREDS2, a 5-year clinical trial, patients with intermediate AMD or late AMD in 1 eye were randomized to 4 treatment groups: lutein zeaxanthin, ω-3 fatty acids, both lutein and ω-3, or placebo
- Long-term Outcomes of Adding Lutein Zeaxanthin and ω-3 Fatty Acids to . . .
Based on the results of the AREDS2 study, the beta carotene component was replaced by lutein zeaxanthin for the development of the revised AREDS supplement, which is now labeled and marketed as the AREDS2 supplement
- How do the AREDS and AREDS2 Differ? - Insight into Low Vision
The two studies differed by the amount of zinc in each formula and the substitution of lutein and zeaxanthin for beta-carotene in the AREDS2 The outcome of the 2 studies were statistically the same: 25% decrease in risk of progression of intermediate ARMD to the more severe advanced ARMD
- Lutein + zeaxanthin and omega-3 fatty acids for age-related macular . . .
Objectives: To determine whether adding lutein + zeaxanthin, DHA + EPA, or both to the AREDS formulation decreases the risk of developing advanced AMD and to evaluate the effect of eliminating beta carotene, lowering zinc doses, or both in the AREDS formulation
- AREDS AREDS2 Ingredients for Macular Degeneration
Lutein and zeaxanthin (L Z) are both carotenoids that accumulate in the macula and retinal pigment epithelial cells and make up part of the macular pigment Supplementation with these carotenoids has been shown to help slow the progression of AMD
- PreserVision AREDS 2 Formulation: Ingredients and Levels
‡ Based on AUC of Lutein and Zeaxanthin compared to original PreserVision® AREDS 2 Soft Gel Provides the convenience of 2 health benefits in one: eye and heart health * Contains the same level of nutrients recommended by the NEI in a great-tasting chewable
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