- A Minimal Regulatory Network of Extrinsic and Intrinsic Factors . . . - PLOS
Author Summary CD4+ T cells orchestrate adaptive immune responses in vertebrates These cells differentiate into several types depending on environmental signals and immunological challenges Once these cells are committed to a particular fate, they can switch to different cell types, thus exhibiting plasticity that enables the immune system to dynamically adapt to novel challenges We integrated available experimental data into a large network that was formally reduced to a minimal
|