- APOE c. -494T gt;C (rs769446) | ALZFORUM
Sequencing nucleotides −1017 to +406 in samples of 75 unrelated Spanish individuals, the authors identified three polymorphisms, including c -494T>C, in the APOE promoter The minor allele, C, is found at a global frequency of 0 07 (gnomAD v2 1 1, August 2022)
- Long-Term Hydromethylthionine Treatment Is Associated with Delayed . . .
Bentham P, Staff RT, Schelter BO, Shiells H, Harrington CR, Wischik CM Long-Term Hydromethylthionine Treatment Is Associated with Delayed Clinical Onset and Slowing of Cerebral Atrophy in a Pre-Symptomatic P301S MAPT Mutation Carrier J Alzheimers Dis 2021;83 (3):1017-1023 PubMed Recommends Please login to recommend the paper
- APOE c. -286T gt;G (rs405509) | ALZFORUM
Sequencing nucleotides −1017 to +406 in samples of 75 unrelated Spanish individuals, the authors identified three new polymorphisms, including c -286T>G, in the APOE promoter Shortly after, c -286T>G was identified in a search for variants that modify the risk of AD associated with APOE4 (Lambert et al , 1998a; Lambert et al , 1998b)
- TPM (Thy-1 PS1. M146V) | ALZFORUM
Brain Res 2004 Aug 13;1017 (1-2):130-6 PubMed Sasmita AO, Ong EC, Nazarenko T, Mao S, Komarek L, Thalmann M, Hantakova V, Spieth L, Berghoff SA, Barr HJ, Hingerl M, Börensen F, Hirrlinger J, Simons M, Stevens B, Depp C, Nave KA Parental origin of transgene modulates amyloid-β plaque burden in the 5xFAD mouse model of Alzheimer's disease
- Could GLP-1 Receptor Agonists Like Semaglutide Treat Addiction . . .
Rubin R Could GLP-1 Receptor Agonists Like Semaglutide Treat Addiction, Alzheimer Disease, and Other Conditions? JAMA 2024 May 14;331 (18):1519-1521 PubMed
- Therapeutics Search | ALZFORUM
How would you like to share? Facebook Twitter LinkedIn Back to the Top Find a Therapeutic By Name Go NSC001 AAB-003 AADvac1 AAV-GAD AAV2-BDNF ABBV-1088 ABBV-552 ABBV-916 ABT 418 ABT-089 ABT-288 ABT-384 ABT-957 ABvac40 ACD856 Acetyl-l-carnitine HCI ACI-24 060 ACI-3024 ACI-7104 056 Acitretin ACP-204 ADEL-Y01 Aduhelm AF 102B Affitope AD02 AGB101 AIT-101 AKST4290 AL002 AL003 AL044 AL101 ALIA-1758
- Functional assessment staging (FAST) in Alzheimers disease . . .
Sclan SG, Reisberg B Functional assessment staging (FAST) in Alzheimer's disease: reliability, validity, and ordinality Int Psychogeriatr 1992;4 Suppl 1:55-69 PubMed Recommends Please login to recommend the paper
- More Private Funding for Alzheimer’s Research | ALZFORUM
Funding also goes to a Phase 1 study of epigallocatechin gallate (EGCG) led by Rafael de la Torre, Hospital del Mar Medical Research Institute, Barcelona, Spain, and a Phase 2 study of a modulator of hepatocyte growth factor, NDX-1017, conducted by Xue Hua of M3 Biotechnology Inc in Seattle
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