- Pharmacokinetics of Single Doses of BI 425809 in Healthy Chinese and . . .
Tsuda Y, Ugai H, Wunderlich G, Shin JG Pharmacokinetics of Single Doses of BI 425809 in Healthy Chinese and Japanese Subjects: A Randomized Study Clin Ther 2019 May;41 (5):961-971 Epub 2019 Apr 17 PubMed Recommends Please login to recommend the paper
- Therapeutics | ALZFORUM
AD Target Therapy Types The two tables below organize the therapeutics within this database by therapy type and proposed target type The number of therapeutics within each category is indicated according to the highest phase each therapeutic has achieved in U S clinical trials For example, if a given therapeutic is in both Phase 2 and Phase 3 trials, it is included in the Phase 3 total
- Therapeutics Search | ALZFORUM
NSC001 AAB-003 AADvac1 AAV-GAD AAV2-BDNF ABBV-1088 ABBV-552 ABBV-916 ABT 418 ABT-089 ABT-288 ABT-384 ABT-957 ABvac40 ACD856 Acetyl-l-carnitine HCI ACI-24 060 ACI-3024 ACI-7104 056 Acitretin ACP-204 ADEL-Y01 Aduhelm AF 102B Affitope AD02 AGB101 AIT-101 AKST4290 AL002 AL003 AL044 AL101 ALIA-1758 Allopregnanolone Alpha-Tocopherol ALX-001 ALZ-101
- Trials Rekindle Interest in Cell Replacement for Parkinson’s
Nature 2025 May;641 (8064):971-977 Epub 2025 Apr 16 Tabar V, Sarva H, Lozano AM, Fasano A, Kalia SK, Yu KK, Brennan C, Ma Y, Peng S, Eidelberg D, Tomishima M, Irion S, Stemple W, Abid N, Lampron A, Studer L, Henchcliffe C Phase I trial of hES cell-derived dopaminergic neurons for Parkinson's disease Nature 2025 Apr 16; Epub 2025 Apr 16
- Tau PET Aligns Spread of Pathology with Alzheimer’s Staging
“Imaging studies will help clarify the contribution of amyloid and tau pathology to cognition, normal aging, and Alzheimer’s dementia,” said Karen Duff, Columbia University, New York, who was not involved in the work “I am happy to see how useful tau PET imaging is going to be in staging and monitoring of disease, which will contribute greatly to diagnosis and drug development ”
- Brain clearance is reduced during sleep and anesthesia. | ALZFORUM
Miao A, Luo T, Hsieh B, Edge CJ, Gridley M, Wong RT, Constandinou TG, Wisden W, Franks NP Brain clearance is reduced during sleep and anesthesia Nat Neurosci 2024 Jun;27 (6):1046-1050 Epub 2024 May 13 PubMed Correction
- Therapeutics Search | ALZFORUM
Search By Attributes Phase 0 Phase 1 Phase 1 2 Phase 2 Phase 2 3 Phase 3 Phase 4 Approved Rejected Inactive Discontinued Not Regulated Withdrawn Target Type Keyword 442 Therapeutics View Results Reset
- In vivo imaging reveals dissociation between caspase activation and . . .
References: Vickers JC, Tan A, Dickson TC Direct determination of the proportion of intra- and extra-cellular neocortical neurofibrillary tangles in Alzheimer's disease Brain Res 2003 May 2;971 (1):135-7 PubMed
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