|
- Pathology Outlines - Lobular carcinoma in situ (LCIS) classic
Distinction between ALH and LCIS is the percentage of the TDLU involved (> 50% in LCIS and < 50% in ALH) with acini that are filled and expanded to qualify as LCIS Some authors use LN terminology to denote the histologic overlap and frequent coexistence of ALH and LCIS (Cancer 1978;42:737)
- Pathology Outlines - Atypical ductal hyperplasia
Atypical ductal hyperplasia is an intraductal clonal epithelial cell proliferation with similar histologic features to (but insufficient involvement or volume for the diagnosis of) low grade ductal carcinoma in situ (DCIS)
- Pathology Outlines - p120 catenin
Stains - p120 catenin p120 catenin (along with α, β and γ catenins) connects the transmembrane protein E-cadherin to the actin cytoskeleton in the cell cytoplasm (Histopathology 2016;68:57)
- Pathology Outlines - E-cadherin
E-cadherin is a transmembrane protein involved in cellular adhesion and polarity maintenance
- Pathology Outlines - Breast
Breast nonmalignant and malignant Page views in 2025 to date (this page and chapter topics): 1,913,729
- Pathology Outlines - LCIS florid
Majority arise in association with classic LCIS or atypical lobular hyperplasia (ALH) (Ann Diagn Pathol 2020;45:151481) Strong association with invasive lobular carcinoma, potentially as a direct precursor (Am J Surg Pathol 2019;43:399, Arch Med Res 2010;41:436, Ann Diagn Pathol 2020;45:151481, Ann Surg Oncol 2011;18:1845)
- Pathology Outlines - Radial scar complex sclerosing lesion
Atypical hyperplasia (ADH, ALH) observed in 21 - 51% (Breast Cancer Res Treat 2008;107:371, Cancer 2003;97:345) In situ or invasive carcinoma may arise within or in association with radial scar complex sclerosing lesions
- 301 Moved Permanently
301 Moved Permanently
|
|
|