Age-related macular degeneration - University of Iowa Age-related macular degeneration (AMD) is the leading cause of blindness in elderly patients [1] and is classified as either non-exudative (i e , dry) or exudative (i e , wet or neovascular) The clinical manifestations of non-exudative AMD range from incidental findings of drusen to geographic atrophy causing significant vision loss, and approximately 15% of AMD patients ultimately transition