- B-cell activating factor - Wikipedia
BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family This cytokine is a ligand for receptors TNFRSF13B TACI, TNFRSF17 BCMA, and TNFRSF13C BAFF-R This cytokine is mainly expressed by myeloid cells, dendritic cells, and stromal cells, and acts as a potent B cell activator
- The BAFF Protein’s Role in Immune Health and Disease
BAFF is an important cytokine that helps regulate both innate and adaptive immune responses It is particularly important for the development, survival, and maturation of B cells, which are specialized white blood cells responsible for producing antibodies that fight off infections
- Current status of BAFF targeting immunotherapy in B-cell . . .
It has multiple receptors, including BCMA, TACI, and BAFF-R, with diverse roles in different cell types BAFF induces B-cell proliferation and immunoglobulin secretion, and acts as a survival factor for immature, naive, and activated B cells
- B-cell activating factor – Knowledge and References – Taylor . . .
B-cell activating factor (BAFF) is a cytokine belonging to the TNF family that is crucial for the generation and maintenance of B cells It acts as a positive regulator of B-cell activation and antibody production
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