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- Derivation and validation of an easy-to-compute trauma . . . - BioMed Central
Background Multiple trauma scores have been developed and validated, including the Revised Trauma Score (RTS) and the Mechanism, Glasgow Coma Scale, Age, and Arterial Pressure (MGAP) score However, these scores are complex to calculate or have low prognostic abilities for trauma mortality Therefore, we aimed to develop and validate a trauma score that is easier to calculate and more accurate
- Lower tidal volume at initiation of mechanical . . . - BioMed Central
Introduction The most appropriate tidal volume in patients without acute respiratory distress syndrome (ARDS) is controversial and has not been rigorously examined Our objective was to determine whether a mechanical ventilation strategy using lower tidal volume is associated with a decreased incidence of progression to ARDS when compared with a higher tidal volume strategy Methods A
- High-dose tranexamic acid reduces blood loss in . . . - BioMed Central
Introduction Our purpose in conducting this study was to determine whether administration of high-dose tranexamic acid (TA) at the time of diagnosis of postpartum haemorrhage (PPH) could reduce blood loss Methods This was a randomised, controlled, multicentred, open-label trial Women with PPH >800 mL following vaginal delivery were randomly assigned to receive TA (loading dose 4 g over 1
- The use of exenatide in severely burned pediatric patients
Introduction Intensive insulin treatment (IIT) has been shown to improve outcomes post-burn in severely burnt patients However, it increases the incidence of hypoglycemia and is associated with risks and complications We hypothesized that exenatide would decrease plasma glucose levels post-burn to levels similar to those achieved with IIT, and reduce the amount of exogenous insulin
- Efficacy of ultrasound-guided radial artery . . . - BioMed Central
Introduction Ultrasound guidance has emerged as an adjunct for central vein catheterization in both adults and children However, the use of ultrasound guidance for radial arterial catheterization has not been well established We conducted a systematic review and meta-analysis to evaluate the efficacy of ultrasound guidance for radial artery catheterization Methods PubMed, Embase, and the
- Accidental catheter removal in critically ill patients . . . - BioMed Central
Use of catheters in critically ill patients is routine In the European Prevalence of Infection in Intensive Care (EPIC) study [1], the following catheters were required in the management of critically ill patients: urinary catheter (75%), central venous catheter (64%), orotracheal tube (62%), arterial catheter (44%) and thoracic drain (14%) Use of catheters carries risks for complications
- Effects of thoraco-pelvic supports during prone . . . - BioMed Central
Introduction This study sought to assess whether the use of thoraco-pelvic supports during prone positioning in patients with acute lung injury acute respiratory distress syndrome (ALI ARDS) improves, deteriorates or leaves unmodified gas exchange, hemodynamics and respiratory mechanics Methods We studied 11 patients with ALI ARDS, sedated and paralyzed, mechanically ventilated in volume
- Gram-negative bacteremia induces greater magnitude of . . . - BioMed Central
Introduction Bacteremia is recognized as a critical condition that influences the outcome of sepsis Although large-scale surveillance studies of bacterial species causing bacteremia have been published, the pathophysiological differences in bacteremias with different causative bacterial species remain unclear The objective of the present study is to investigate the differences in
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