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  • Bioavailability and duration of insufflated heroin?
    I was wondering if anyone knew what the bioavailability of (powder) heroin is when you snort it, or at the very least, why it's hard for me to find accurate info on this anywhere on BL the internet Also, how long do the effects of insufflated heroin last, compared to say a recreational dose of
  • Oxycodone insufflation bioavailability vs. oral bioavailability . . .
    The bioavailability of oral administration of Oxycodone averages 60–87%, with rectal administration yielding the same results; intranasal varies between individuals with a mean of 46%
  • Bupe - Plugging Suboxone? | Bluelight. org
    "the oral bioavailability for buprenorphine is state to be 10%" "due to extensive first-pass metabolism, buprenorphine has very poor oral bioavailability (10% of the intravenous route) if swallowed"
  • Oxycodone Snorting vs Eating. (How much is wasted Bioavailability)
    My question is a two parter; 1) What is the bioavailability for snorting vs eating oxycodone 30mg IR? 2) Is there a real difference in terms of the high with each method or is this all just my own little mental habitual ritual?
  • How to improve bioavailability of N-acetylcysteine - Bluelight. org
    Low bioavailability of NAC is one of the major limitations for maximizing its effects on oxidative stress-related diseases Giustarini et al (2012) reported that esterification of the carboxyl group of NAC to produce N-acetylcysteine ethyl ester (NACET) would increase the lipophilicity of NAC as the mechanism of increasing its pharmacokinetics
  • Bioavailability of oral cocaine? - Bluelight. org
    The absolute oral cocaine bioavailability was determined pharmacokinetically (F) and pharmacodynamically (Fsrr and Frr) Results IV and PO cocaine increased the shorter response rate and decreased the reinforcement rate in a dose- and time-related fashion, which mirrored the respective prototypical serum cocaine CTPs
  • Opioids - Morphine rectally (plugged) dose | Bluelight. org
    There appears to be some conjecture regarding the bioavailability of rectally-administered Morphine For that matter, routes of administration with Morphine could qualify as unusual
  • can I snort clonazepam? - Bluelight. org
    The bioavailability of any medication is the amount of the drug taken that gets absorbed and activated inside the body In the case of Klonopin, the target areas are the brain and the nervous system Thus, the bioavailability of Klonopin would be the amount of the substance able to create a sedative effect on the nervous system




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