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- CD46 - Wikipedia
CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a protein which in humans is encoded by the CD46 gene [5]
- CD46 Gene - GeneCards | MCP Protein | MCP Antibody
CD46 (CD46 Molecule) is a Protein Coding gene Diseases associated with CD46 include Hemolytic Uremic Syndrome, Atypical 2 and Genetic Atypical Hemolytic-Uremic Syndrome Among its related pathways are Complement cascade and Immune response Lectin induced complement pathway
- CD46 - an overview | ScienceDirect Topics
CD46 is a widely expressed transmembrane protein that was initially identified as binding and inactivating C3b and C4b complement products CD46 is also recognized by several human pathogens that use this surface protein as an entry receptor
- Membrane cofactor protein (MCP; CD46): deficiency states and pathogen . . .
Membrane cofactor protein (MCP; CD46), a ubiquitously expressed complement regulatory protein, serves as a cofactor for serine protease factor I to cleave and inactivate C3b and C4b deposited on host cells
- CD46: expanding beyond complement regulation: Trends in Immunology
CD46 is a type I transmembrane glycoprotein that is expressed on most tissues as four major isoforms derived by alternative splicing of a single gene The N-terminus of each isoform consists of four complement control protein repeats (CCPs), and CCPs 1, 2 and 4 each bear one N-linked complex sugar
- Complement regulator CD46: genetic variants and disease . . . - PubMed
Membrane cofactor protein (MCP; CD46) is an ubiquitously expressed complement regulatory protein that protects host cells from injury by complement This type-I membrane glycoprotein serves as a cofactor for the serine protease factor I to mediate inactivation of C3b and C4b deposited on host cells …
- Identification and quantification of complement regulator CD46 on . . .
CD46 is a cell-surface regulatory molecule that prevents lysis of autologous human cells by activated complement It has been well characterized on leucocytes, reproductive cells and various cultured cell lines and is considered to be ubiquitously expressed
- CD46 - an overview | ScienceDirect Topics
CD46 is a complement regulator that serves as a cellular pilus receptor for the human pathogens Neisseria gonorrhoeae and Neisseria meningitidis
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