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- DPYD gene: MedlinePlus Genetics
The DPYD gene provides instructions for making an enzyme called dihydropyrimidine dehydrogenase, which is involved in the breakdown of molecules called uracil and thymine when they are not needed Learn about this gene and related health conditions
- DPYDZ - Overview: Dihydropyrimidine Dehydrogenase, DPYD Full Gene . . .
Identifying common and rare variants associated with decreased or absent dihydropyrimidine dehydrogenase (DPD) enzyme activity in individuals with suspected DPD deficiency This is a pharmacogenomics test associated with 5-fluorouracil and capecitabine drug sensitivity
- DPYD Gene - GeneCards | DPYD Protein | DPYD Antibody
DPYD (Dihydropyrimidine Dehydrogenase) is a Protein Coding gene Diseases associated with DPYD include Dihydropyrimidine Dehydrogenase Deficiency and Dihydrolipoamide Dehydrogenase Deficiency Among its related pathways are Fluoropyrimidine activity and Metabolism of nucleotides
- 512275: DPYD Genotyping | Labcorp
Substantial evidence supports the use of DPYD genotyping for guiding fluoropyrimidine dosage use Variation in the DPYD gene can result in normal (NM), intermediate (IM) and poor (PM) drug-metabolizing genotypes
- What is a DPYD (dihydropyrimidine dehydrogenase) test and why do I need . . .
What is the DPYD test? The DPYD test is a simple blood test It is sometimes called a DPD test The blood test checks for the gene changes that are most likely to cause low levels of the DPD enzyme
- Dihydropyrimidine dehydrogenase (NADP+) - Wikipedia
In enzymology, a dihydropyrimidine dehydrogenase (NADP+) (EC 1 3 1 2) is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are 5,6-dihydrouracil and NADP +, whereas its 3 products are uracil, NADPH, and H +
- Entry - *612779 - DIHYDROPYRIMIDINE DEHYDROGENASE; DPYD - OMIM
The DPYD gene encodes dihydropyrimidine dehydrogenase (EC 1 3 1 2), the initial and rate-limiting enzyme in the catabolism of the pyrimidine bases uracil and thymine (Van Kuilenburg et al , 1999)
- DPYD - MyPathologyReport
What does the DPYD gene do? The DPD enzyme made by the DPYD gene is responsible for breaking down fluoropyrimidine drugs, which include 5-FU and capecitabine These drugs are commonly used to treat cancers of the colon, breast, stomach, esophagus, and head and neck
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