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- Death receptor 4 - Wikipedia
Death receptor 4 (DR4), also known as TRAIL receptor 1 (TRAILR1) and tumor necrosis factor receptor superfamily member 10A (TNFRSF10A), is a cell surface receptor of the TNF-receptor superfamily that binds TRAIL and mediates apoptosis [5][6]
- Definition of DR4 - NCI Dictionary of Cancer Terms
A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer cells An increase in the amount or activity of DR4 on cancer cells may kill more cells
- What are DR4 agonists and how do they work? - Patsnap
DR4, or Death Receptor 4, is a member of the tumor necrosis factor receptor (TNFR) superfamily that plays a crucial role in mediating apoptosis, the process of programmed cell death This receptor has garnered significant attention for its potential use in oncology and other medical fields
- Death Receptor 4 - an overview | ScienceDirect Topics
Death receptor 4 (DR4) is defined as a member of the tumor necrosis factor (TNF) receptor superfamily that mediates apoptosis in response to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) binding, contributing to extrinsic apoptosis pathways in cells
- Expression of Death Receptor 4 Is Positively Regulated by MEK ERK AP-1 . . .
Death receptor 4 (DR4) is a cell surface receptor for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and triggers apoptosis upon ligation with TRAIL or aggregation
- Differential Regulation of the TRAIL Death Receptors DR4 and DR5 by the . . .
From previous studies the regulation of the DR4 and DR5 cell-death pathways appeared similar; nevertheless in this study we screened a library of small interfering RNA (siRNA) for genes, which when silenced, differentially affect DR4- vs DR5-mediated apoptosis
- Death Receptors DR4 and DR5 Undergo Spontaneous and Ligand . . . - Frontiers
Here we have compared the kinetics of TRAIL-mediated internalization and subsequent recycling of DR4 and DR5 in resistant (HT-29 and A549) and sensitive (HCT116 and Jurkat) tumor cell lines of various origin
- 400G Optical Modules Explained: SR4 Vs. DR4 Vs. FR4 Vs. LR4
Key differences between SR4, DR4, FR4, and LR4 400G optical modules Expert advice from Asterfusion engineers to optimize your data center network
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