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- Welcome to ERSO | erso
ERSO delivers reliable and efficient services, allowing faculty, staff and students to focus on the research and academic enterprise We are a service-oriented operation comprised of experts committed to delivering solutions and striving for continuous improvement
- Erso Diagnostics
Relevant clinical information and advanced analytical technologies are applied for each specimen Today, Erso continues to introduce evolving technology and science— with the goal of providing our customers with better, more actionable data and ever-more accurate results
- CCIL Scientists’ Single Dose Breast Cancer Treatment Induces Complete . . .
Experiments so far suggest that ErSO-TFPy is safe and potent enough for single dose efficacy, possibly eliminating the need for chronic treatment In addition to this impressive fact, the drug is also incredibly powerful even against large, late-stage tumors in mice
- A small-molecule activator of the unfolded protein response . . . - PubMed
Seeking to target these drug-resistant cancers, we report the discovery of a compound, called ErSO, that activates the anticipatory unfolded protein response (a-UPR) and induces rapid and selective necrosis of ERα-positive breast cancer cell lines in vitro
- Breast Cancer Tumors in Mice Eliminated by Single-Dose ErSO-TFPy
For this study, the researchers tested a modified derivative of a previously developed small molecule, ErSO, which had shown potential for treating ER+ breast cancer but also produced undesirable side effects
- Breakthrough Single-Dose Drug Wipes Out Breast Tumors in Mice Without . . .
In small tumors, a single dose of ErSO-TFPy eliminated them entirely, while the same dose significantly shrank large tumors In both mice and rats, no deleterious side effects were observed
- New approach eradicates breast cancer in mice | ScienceDaily
When ErSO binds to the estrogen receptor, it upregulates a cellular pathway that prepares cancer cells for rapid growth and protects them from stress
- ErSO | a-UPR Activator | MedChemExpress
ErSO is a selective anticipatory unfolded protein response (a-UPR) activator ErSO acts through ERα to elicit strong and sustained cytotoxic activation of the a-UPR
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