- EZH2 - Wikipedia
EZH2 inhibits genes responsible for suppressing tumor development, and blocking EZH2 activity may slow tumor growth EZH2 has been targeted for inhibition because it is upregulated in multiple cancers including, but not limited to, breast, [10] prostate, [11] melanoma, [12] and bladder cancer [13]
- EZH2 Gene - GeneCards | EZH2 Protein | EZH2 Antibody
EZH2 (Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit) is a Protein Coding gene Diseases associated with EZH2 include Weaver Syndrome and Ezh2-Related Overgrowth
- 医药魔方 | EZH2：表观遗传，枯树逢春 - 知乎
EZH2（enhancer of zeste homolog）全称为“调味增强子同源物2”，属于 PcG蛋白 （Polycomb group protein）中关键成员之一, 也是pRC2（Polycomb Repressive Complex 2，多梳抑制复合体2）的核心亚基之一，具有组蛋白甲基化转移酶活性, 在表观遗传修饰过程中扮演重要角色。
- EZH2: a novel target for cancer treatment - PubMed
In this review, we summarize the structure and action modes of EZH2, focusing on up-to-date findings regarding the role of EZH2 in cancer initiation, progression, metastasis, metabolism, drug resistance, and immunity regulation
- EZH2在肿瘤中的作用及其抑制剂的研究进展
Therefore, EZH2 is considered to be a promising therapeutic target for tumor treatment Currently, the development and clinical trials of small molecule inhibitors targeting EZH2 have emerged as a prominent area of research
- EZH2 expression in hepatocellular carcinoma and its . . . - Nature
EZH2 was overexpressed in HCC and was associated with advanced tumor stage, poor prognosis, Th2 and dendritic cell infiltration, and promoter hypermethylation
- EZH2_百度百科
EZH2基因定位于7号染色体q35区域，作为多梳抑制复合体2（PRC2）的核心催化亚基，通过催化组蛋白H3K27三甲基化（H3K27me3）调控基因沉默。 该基因异常表达与多种肿瘤相关，包括血液系统恶性肿瘤和实体瘤，临床研究显示其可作为预后标志物和治疗靶点。
- EZH2基因的功能与作用机制解析 - 八方基因
本文详细介绍了EZH2基因的功能与作用机制，涵盖其生物学功能、信号通路、与疾病的关系等方面，帮助读者全面理解这一重要的表观遗传调控因子。
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