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- HBB Gene - GeneCards | HBB Protein | HBB Antibody
HBB (Hemoglobin Subunit Beta) is a Protein Coding gene Diseases associated with HBB include Sickle Cell Disease and Beta-Thalassemia, Dominant Inclusion Body Type Among its related pathways are Innate Immune System and Erythrocytes take up carbon dioxide and release oxygen Gene Ontology (GO) annotations related to this gene include iron ion binding and oxygen binding An important paralog
- HBB gene: MedlinePlus Genetics
The HBB gene provides instructions for making a protein called beta-globin Beta-globin is a component (subunit) of a larger protein called hemoglobin, which is located inside red blood cells In adults, hemoglobin typically consists of four protein subunits: two subunits of beta-globin and two subunits of a protein called alpha-globin, which is produced from another gene called HBA Each of
- HBB hemoglobin subunit beta [Homo sapiens (human)] - Gene - NCBI
Gene target information for HBB - hemoglobin subunit beta (human) Find diseases associated with this biological target and compounds tested against it in bioassay experiments
- Hbb gene - functions, mutations, and implications - Genetics
The Hbb gene, also known as the human beta-globin gene, plays a crucial role in the production of hemoglobin, an essential protein in the human body Hemoglobin is responsible for carrying oxygen from the lungs to the body’s tissues and carrying carbon dioxide back to the lungs for exhalation The hbb gene is located on chromosome 11 and is composed of three subunits: alpha, beta, and gamma
- Hemoglobin Disorders - University of Utah
Genetic Science Learning CenterThe HBB gene, on chromosome 11, codes for beta-globin protein Two molecules of beta-globin combine with two molecules of alpha-globin to form hemoglobin Hemoglobin protein is a major part of red blood cells It gives blood its color and allows it to carry oxygen The red comes from hemes—iron-containing molecules that sit within each globin protein The heme
- Entry - *141900 - HEMOGLOBIN--BETA LOCUS; HBB - OMIM
The alpha (HBA1, 141800; HBA2, 141850) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, HbA Mutant beta globin that sickles causes sickle cell disease (603903) Absence of beta chain causes beta-zero-thalassemia Reduced amounts of detectable beta globin causes beta-plus-thalassemia For clinical purposes, beta-thalassemia (613985) is
- Investigation of mutations in the HBB gene using the 1,000 . . .
Mutations in the HBB gene are responsible for several serious hemoglobinopathies, such as sickle cell anemia and β-thalassemia Sickle cell anemia is one of the most common monogenic diseases worldwide Due to its prevalence, diverse strategies have
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