- Hexafluoro-2-propanol - Wikipedia
Hexafluoro-propan-2-ol is a speciality solvent for organic synthesis, particularly for reactions involving oxidations and strong electrophiles For example, HFIP enhances the reactivity of hydrogen peroxide as applied to Baeyer-Villiger oxidation of cyclic ketones [1]
- 1,1,1,3,3,3-Hexafluoro-2-propanol = 99 920-66-1 - MilliporeSigma
1,1,1,3,3,3-Hexafluoro-2-propanol is a solution-phase peptide chemistry solvent [1] This fluorinated polar solvent of high ionizing power facilitates Friedel–Crafts-type reactions, using covalent reagents in the absence of a Lewis acid catalyst [2]
- The rise and future of hexafluoroisopropanol as a solvent
Recent years have seen a surge in the use of HFIP in acid catalysis due to its unique solvent properties, such as the formation of catalytically active self-assembled H-bond clusters and its ability to extend the lifetime of cationic intermediates or to serve as a cation sink
- 1,1,1,3,3,3-Hexafluoro-2-propanol | 920-66-1 - ChemicalBook
Hexafluoroisopropanol is used to produce high-end chemicals, such as fluorinated surfactants, fluorinated emulsifier and fluorinated medicine, etc HFIP is used as a solvent or cleaner in electronic industry
- Hexafluoroisopropanol as a highly versatile solvent - Nature
1,1,1,3,3,3-Hexafluoroisopropanol (HFIP) has recently become a very popular solvent or additive with applications across the spectrum of chemistry Analysis shows that it possesses a wide range
- Sixty Solvents: - University of Rochester
Hexafluoroisopropanol (HFIP) is a clear, dense, low viscosity liquid with a volatile pungent odour This fluorinated alcohol finds use as solvent and synthetic intermediate
- Hexafluoroisopropanol: A Remarkably Flexible Solvent for Proteins . . .
The presence of both a hydroxyl (-OH) group and highly electronegative fluorine atoms creates a balance between hydrogen bonding capacity and hydrophobic character, making HFIP an effective solvent for biomolecular applications
- HFIP in Organic Synthesis | Chemical Reviews - ACS Publications
1,1,1,3,3,3-Hexafluoroisopropanol (HFIP) is a polar, strongly hydrogen bond-donating solvent that has found numerous uses in organic synthesis due to its ability to stabilize ionic species, transfer protons, and engage in a range of other intermolecular interactions
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