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  • JCI - Welcome
    In this issue of the JCI, Khan et al investigated FATP2 in glycemic control In db db mice, global FATP2 deletion reduced plasma glucose via sustained insulin secretion, with expression restricted to pancreatic α cells
  • JCI - About the Journal of Clinical Investigation
    You may submit manuscripts for consideration solely by the JCI or select the Dual-Journal Submission option to have your manuscript evaluated by the JCI and JCI Insight Start your submission by accessing your JCI author account If you don’t have an account yet, sign up here
  • JCI - Author Information Center
    JCI is a Gold Open Access journal and deposits all published research articles in PubMed Central, which satisfies the NIH Public Access Policy and other similar funding agency requirements
  • JCI - Welcome
    Volume 135, Issue 23November 17, 2025
  • JCI Insight - Welcome
    Michelle S M A Damen, … , Maria E Moreno-Fernandez, Senad Divanovic Published November 24, 2025 Citation Information: JCI Insight 2025; 10 (22):e185914 https: doi org 10 1172 jci insight 185914
  • JCI - Volume 135, Issue 22
    In this issue of the JCI, Okaa et al report that endonuclease 2 (Eng2), an antigen shared by the Blastomyces, Histoplasma, and Coccidioides species of fungi, elicits protective immunity in mice against blastomycosis, histoplasmosis, and coccidioidomycosis
  • JCI - Welcome
    On October 1, 1924, the American Society of Clinical Investigation published the first issue of the JCI Over the last 100 years, JCI ’s mission has been to provide a forum for research exploring mechanisms underlying human health and disease
  • JCI Insight - Author Information Center
    JCI Insight and the American Society for Clinical Investigation (ASCI) are dedicated to upholding the highest standards of integrity and ethical conduct in research, and in its evaluation and related communication




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