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- Structured Exercise after Adjuvant Chemotherapy for Colon Cancer
Preclinical and observational studies suggest that exercise may improve cancer outcomes However, definitive level 1 evidence is lacking In this phase 3, randomized trial conducted at 55 centers,
- Tarlatamab in Small-Cell Lung Cancer after Platinum-Based Chemotherapy
Tarlatamab is a bispecific T-cell engager immunotherapy that concomitantly targets delta-like ligand 3 (DLL3), which is expressed on the surface of cancer cells in 85 to 96% of patients with small
- Tirzepatide as Compared with Semaglutide for the Treatment of Obesity
In this phase 3b, open-label, controlled trial, adult participants with obesity but without type 2 diabetes were randomly assigned in a 1:1 ratio to receive the maximum tolerated dose of
- Lepodisiran - The New England Journal of Medicine
Elevated lipoprotein(a) concentrations are associated with atherosclerotic cardiovascular disease The safety and efficacy of lepodisiran, an extended-duration, small interfering RNA targeting hepa
- Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 . . .
Letter to the Editor: Serum creatinine-to-albumin ratio as a predictor of 28-day mortality in critically ill patients with ischemic stroke: A retrospective cohort study, Journal of Clinical
- Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist, in Early . . .
Orforglipron is a small-molecule, nonpeptide glucagon-like peptide-1 (GLP-1) receptor agonist in clinical development for type 2 diabetes and weight management Additional data on the efficacy and
- Phase 3 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis
A total of 1721 patients (1680 adults and 41 adolescents) underwent randomization and received brensocatib or placebo The annualized rate of pulmonary exacerbations was 1 02 in the 10-mg
- Mepolizumab to Prevent Exacerbations of COPD with an Eosinophilic . . .
An estimated 20 to 40% of patients with chronic obstructive pulmonary disease (COPD) have signs of eosinophilic inflammation, a condition that is characterized by an increased blood eosinophil
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