- 5-Year CROWN Data Show Continued Benefit With Lorlatinib in Advanced . . .
At 5-year follow-up, lorlatinib continues to show progression-free survival (PFS) benefit versus crizotinib in patients with previously untreated advanced ALK -positive non–small cell lung cancer (NSCLC) with no new safety signals
- ALK+ next treatment option | CancerGRACE
- Discontinue Lorlatinib due to probable drug induced Fibrotic lung condition? - If Fibrotic lung is a TKI drug induced condition, what is the next best course of action?
- Lorlatinib or PF-06463922 - 1272666 | CancerGRACE
I am nearly 5 years living with ALK+ stage IV disease Brain mets occurred in 5 2014 - asymptomatic Decreased with switch to ceretinib 2 15 brain mets grew - treated with SRS 10 1 - more brain mets with symptoms, treated with RT to cerebellum 12 1- Started on lorlatinib (PF-06463922) Experiencing leg edema, high cholesterol levels, increased PN in feet
- If Lorlatinib doesnt work? - 1290044 - CancerGRACE
And in another post, he stated that he hadn't used lorlatinib (as of January 2016) since it was still an investigational agent In light of this statement, it may just be too early to know whether one of these agents is likely to be effective after use of the other, and which sequence would be preferred
- ASCO 2017 - Lung Cancer - Sequencing Treatments for ALK+ Lung Cancer in . . .
Drs H Jack West, Matthew Gubens, and Jyoti Patel, gathered post ASCO 2017 to discuss new information regarding lung cancer In this video, the doctors discuss Sequencing Treatments for ALK+ Lung Cancer in a Crowded Field - Is there a place for Lorlatinib?
- 2022 Targeted Therapies Patient Forum Advances ALK+, RET+, and MET+ NSCLC
2022 Targeted Therapies Patient Forum Advances ALK+, RET+, and MET+ NSCLC Dr Fred Hirsch (Executive Director, Center for Thoracic Oncology at Tisch Cancer Institute, Mount Sinai, Professor of Medicine, Icahn School of Medicine, Associate Director, Biomarker Discovery for TCI)
- Unlocking Precision in Lung Cancer: Understanding and Overcoming . . .
Lorlatinib: A third-generation ALK inhibitor, lorlatinib has demonstrated activity against various ALK resistance mutations, making it an important treatment option for patients who have progressed on earlier-generation ALK inhibitors
- lorlatinib | CancerGRACE
Drs H Jack West, Matthew Gubens, and Jyoti Patel, gathered post ASCO 2017 to discuss new information regarding lung cancer In this video, the doctors discuss Sequencing Treatments for ALK+ Lung Cancer in a Crowded Field - Is there a place for Lorlatinib?
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