|
- Myc - Wikipedia
The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN) c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this family, due to homology with the viral gene v-myc
- The MYC oncogene — the grand orchestrator of cancer growth and immune . . .
MYC has two paralogues: MYCL and MYCN The initially held view was that MYC is ubiquitously involved in human cancers (both haematological and solid), whereas L-MYC is associated with small-cell lung cancer and N-MYC with neuroblastoma
- MYC Gene - GeneCards | MYC Protein | MYC Antibody
MYC (MYC Proto-Oncogene, BHLH Transcription Factor) is a Protein Coding gene Diseases associated with MYC include Burkitt Lymphomaand High-Grade B-Cell Lymphoma Double-Hit Triple-Hit
- MYC in cancer: from undruggable target to clinical trials
This Review provides an overview of the various strategies to inhibit MYC, focusing on the most recently described inhibitors and those that have reached clinical trials
- Myc - an overview | ScienceDirect Topics
MYC is a proto-oncogene that encodes a powerful regulator of transcription and cellular programs essential for normal development, as well as the growth and survival of various types of cancer cells MYC rearrangement and amplification is a common cause of hematologic malignancies
- MYC: there is more to it than cancer - PMC
MYC is a pleiotropic transcription factor involved in multiple cellular processes While its mechanism of action and targets are not completely elucidated, it has a fundamental role in cellular proliferation, differentiation, metabolism, ribogenesis, and bone and vascular development
- MYC on the Path to Cancer: Cell
MYC produces the transcription factor Myc, which dimerizes with Max and binds target DNA sequences or E boxes (with the sequence 5′-CANNTG-3′) to regulate transcription of genes involved in cell growth and proliferation
- The effects of MYC on tumor immunity and immunotherapy
The abnormal expression of MYC is one of the most common carcinogenic events in human cancer MYC modulates immune effector cells and immune regulatory factors in the tumor immune
|
|
|