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- POLM Gene - GeneCards | DPOLM Protein | DPOLM Antibody
POLM (DNA Polymerase Mu) is a Protein Coding gene Diseases associated with POLM include Congenital Myopathy 2A, Typical, Autosomal Dominant and Xeroderma Pigmentosum, Variant Type
- Entry - *606344 - POLYMERASE, DNA, MU; POLM - OMIM
POLM is a template-dependent DNA polymerase closely related to the lymphoid-specific enzyme terminal deoxynucleotidyltransferase (TDT; 187410) POLM appears to participate in the processing of DNA ends during immunoglobulin (Ig) gene rearrangement (Bertocci et al , 2003)
- POLM DNA polymerase mu [Homo sapiens (human)] - Gene - NCBI
Gene target information for POLM - DNA polymerase mu (human) Find diseases associated with this biological target and compounds tested against it in bioassay experiments
- POLM inhibits porcine epidemic diarrhea virus replication by degrading . . .
This study concerned a host factor POLM (a DNA polymerase family member) that exerts an anti-viral effect against PEDV proliferation Our results indicated that POLM expression was increased following PEDV infection and was regulated by the transcription factor FOXA1
- POLM variant G312R promotes ovarian tumorigenesis through genomic . . .
We uncover the POLM G312R mutation as a driver of genomic instability in ovarian cancer via aberrant ribonucleotide incorporation We reveal that POLM G312R upregulates COL11A1 and activates NF-κB signaling, contributing to tumor progression and chemoresistance
- DNA polymerase mu (Pol μ), homologous to TdT, could act as a DNA . . .
The human gene (POLM) coding for Pol μ was mapped initially to chromosome 7 by using a panel of human–rodent somatic cell hybrids (see Materials and methods)
- POLM - vesuvius. wi. mit. edu
Each montage below shows randomly selected individual cell images for the same target gene separated by sgRNA, along with an example montage of cells expressing a non-targeting negative control sgRNA at the bottom sgRNA labels in the montages correspond to the numbered sgRNA sequences in the gene info table above The DNA (blue) and tubulin (green) channels are displayed by default, with
- Structural snapshots of human DNA polymerase μ engaged on a . . . - Nature
Polymerase μ (Polμ) participates in the repair of DNA double-strand breaks (DSBs) via the nonhomologous end-joining (NHEJ) pathway Here, the authors determine the crystal structure of a pre
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