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- POLM Gene - GeneCards | DPOLM Protein | DPOLM Antibody
POLM (DNA Polymerase Mu) is a Protein Coding gene Diseases associated with POLM include Congenital Myopathy 2A, Typical, Autosomal Dominant and Xeroderma Pigmentosum, Variant Type
- DNA polymerase mu - Wikipedia
DNA polymerase mu DNA polymerase mu is a polymerase enzyme found in eukaryotes In humans, this protein is encoded by the POLM gene [5]
- Entry - *606344 - POLYMERASE, DNA, MU; POLM - OMIM
POLM is a template-dependent DNA polymerase closely related to the lymphoid-specific enzyme terminal deoxynucleotidyltransferase (TDT; 187410) POLM appears to participate in the processing of DNA ends during immunoglobulin (Ig) gene rearrangement (Bertocci et al , 2003)
- POLM DNA polymerase mu [Homo sapiens (human)] - Gene - NCBI
Gene target information for POLM - DNA polymerase mu (human) Find diseases associated with this biological target and compounds tested against it in bioassay experiments
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- DNA polymerase mu (Pol μ), homologous to TdT, could act as a DNA . . .
Based on the correspondence of this marker with the GCK gene, the POLM gene has been mapped within band 7p13 This region constitutes one of the four known fragile sites in lymphocytes, with a high incidence of molecular alterations such as deletions, inversions and translocations
- POLM variant G312R promotes ovarian tumorigenesis through genomic . . .
Our investigation elucidates the role of the DNA polymerase mu (POLM), especially G312R mutation, in propelling oncogenesis through dual pathways POLM G312R markedly augments the ribonucleotide insertion capability of POLM, precipitating genomic instability
- POLM inhibits porcine epidemic diarrhea virus replication by degrading . . .
This study concerned a host factor POLM (a DNA polymerase family member) that exerts an anti-viral effect against PEDV proliferation Our results indicated that POLM expression was increased following PEDV infection and was regulated by the transcription factor FOXA1
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