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- Pemphigus Vulgaris: A Complete Overview — DermNet
Pemphigus vulgaris is a rare autoimmune disease that is characterised by painful blisters and erosions on the skin and mucous membranes, most commonly inside the mouth It accounts for 70% of all pemphigus cases worldwide Images below show mucosal lesions
- Pemphigus Foliaceus: Causes, Symptoms and Images — DermNet
The pemphigus family are rare autoimmune blistering diseases affecting the skin and mucous membranes The primary aim of treatment is to prevent bacterial infection; spontaneous remission may occur in patients while in others, the problem may persist for several years
- Paraneoplastic pemphigus - DermNet
Paraneoplastic pemphigus (PNP) is a rare, autoimmune, mucocutaneous, blistering disease that is almost always associated with a confirmed or occult neoplasm The cause of PNP is not completely understood
- Nikolskys Sign - DermNet
Using Nikolsky’s original definition strictly, his eponymous sign is the physical splitting of the epidermis creating an erosion (partial loss of the epidermis) following the application of a shearing force to the surface of the skin seen in pemphigus foliaceus However, with time the use of the sign has broadened to include other intraepidermal disorders including pemphigus vulgaris and it
- Oral blistering diseases - DermNet
Oral pemphigus Pemphigus is a term originally derived from the Greek word, pemphix, meaning bubble or blister It describes a group of blistering disorders characterised by antibodies directed against intercellular substance, which is found between epithelial cells (called keratinocytes in the skin)
- Drug-induced pemphigus - DermNet
The diagnosis of pemphigus is confirmed by its characteristic intraepidermal blistering when seen on histology of a skin biopsy, and the presence of typical antibodies on direct immunofluorescence Circulating pemphigus antibodies against desmoglein 1 and or desmoglein 3 may be detected on serology How is drug-induced pemphigus treated?
- Hailey-Hailey disease (benign familial pemphigus) - DermNet
What is benign familial pemphigus? Benign familial pemphigus is also known as Hailey–Hailey disease It is a rare hereditary blistering skin disease first described by the Hailey brothers in 1939 Unrelated to pemphigus vulgaris, Hailey-Hailey disease is not an autoimmune condition and has a differing prognosis
- Bullous Pemphigoid: Causes, Symptoms, and Treatment — DermNet
Bullous pemphigoid is the most common form of autoimmune subepidermal blistering disease Treatment for bullous pemphigoid is usually needed for several years In many cases, the pemphigoid eventually completely clears up, and the treatment can be stopped
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