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- Answered: 11. INTERPRET THE DATA Phosphofructokinase is an . . . - bartleby
11 INTERPRET THE DATA Phosphofructokinase is an enzyme that acts on fructose 6- phosphate at an early step in glucose breakdown Regulation of this enzyme controls whether the sugar will continue on in the glycolytic pathway Considering this graph, under which condition is phosphofructokinase more active? Given what you know about glycolysis and regulation of metabolism by this enzyme
- Answered: Although both hexokinase and phosphofructokinase catalyze . . .
Although both hexokinase and phosphofructokinase catalyze irreversible steps in glycolysis and the hexokinase-catalyzed step is first, phosphofructokinase is nonetheless the pacemaker of glycolysis What does this information tell you about the fate of the glucose 6-phosphate formed by hexokinase? Glucose 6-phosphate must be unstable and release its phosphoryl group over time Glucose 6
- Answered: Exercise 5. 2 Consider the equilibrium reaction . . . - bartleby
Exercise 5 2 Consider the equilibrium reaction catalysed by two enzymes, hexokinase, and phosphofructokinase, producing Glucose-6-phosphate (G6P) and Acetate (ACE): Glucose + Acetyl phosphate G6P + ACE A mixture containing 40 mM glucose and 25 mM acetyl phosphate was incubated with the enzymes and a catalytic amount of ATP at pH 7 0 and 25C until equilibrium occurs Calculate the equilibrium
- Answered: The inhibition of PFK-1 by ATP diminishes when the . . . - bartleby
Transcribed Image Text: The graph shows the effect of ATP on the allosteric enzyme phosphofructokinase-1 (PFK-1) PFK-1 activity (% of Vmax) 100 80 60 40 20 0 Low [ADP] [ATP] High [ADP] For a given concentration of fructose 6-phosphate, the PFK-1 activity increases with increasing concentrations of ATP, but there is a point beyond which increasing the concentration of ATP inhibits the enzyme
- Answered: Phosphofructokinase (PFK) activity is altered by . . . - bartleby
Phosphofructokinase (PFK) activity is altered by changes in the energy state of the cell Under high AMP and low ATP levels, PFK will be: (Select all that apply) 0000 Activated because AMP is an allosteric activator of PFK Inhibited because AMP is an allosteric inhibitor of PFK Inhibited as low ATP levels inhibit glycolysis Activated because
- In liver, the accumulation of which of the following metabolite . . .
In liver, the accumulation of which of the following metabolite attenuates the inhibitory of ATP on phosphofructokinase? * Fructose-2,6-Bisphosphate Fructose-1,6-Bisphosphate Glucose-6-Phosphate Citrate
- Answered: 6. In principle, a futile cycle that includes . . . - bartleby
6 In principle, a futile cycle that includes phosphofructokinase (PFK) and fructose-2,6- bisphosphatase (F-1,6BPase) could be used to generate heat How? The could be used to warm tissues For instance, certain bumblebees have been reported to use such a futile cycle to warm their flight muscles on cool mornings Scientists undertook a series of experiments to determine if several species of
- Answered: 5. There is reciprocal regulation of glycolytic and . . .
D) The phosphofructokinase-1 reaction is endergonic This regulation allows control of the direction of net metabolite flow through the pathway 5 There is reciprocal regulation of glycolytic and gluconeogenic reactions interconverting fructose-6-phosphate and fructose-1,6-bisphosphate
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