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- AUSTRALIAN PRODUCT INFORMATION COLOFAC
Following oral administration of 3H and 14C labelled mebeverine hydrochloride in man, absorption was followed by the appearance in the plasma of veratric acid and an oxidised metabolite of the mebeverine alcohol moiety of the drug, mebeverinic acid
- NSAID hypersensitivity guideline
The majority of NSAID adverse drug reactions (ADRs) are pharmacological or dose-related side effects, with hypersensitivity reactions accounting approximately 20% of all NSAID-related ADRs (5)
- Mebeverine hydrochloride
Exposure to small quantities may induce hypersensitivity reactions characterized by acute bronchospasm, hives (urticaria), deep dermal wheals (angioneurotic edema), running nose (rhinitis) and blurred vision
- Hypersensitivity Reactions
Learning Objectives By the end of this lecture you will be able to: 1 List the four types of hypersensitivity reactions 2 Describe the mechanism of each hypersensitivity reaction 3 Understand the clinical manifestations and managements of some hypersensitivity reactions
- Summary of Product Characteristic Mebeverine Hydrochloride
Mechanism of action and pharmacodynamic effects Mebeverine is a mucosotropic antispasmodic with a direct effect on the smooth muscle of the gastrointestinal tract, without affecting normal gut motility
- Practical Guidelines for Diagnosing Hypersensitivity . . .
for the diagnosis and management of hypersensitivity reactions to nonsteroidal anti-inflammatory d ugs (NSAIDs) The findings presented in the document are based on the agreement reached between the participants Applic
- Classification and management of hypersensitivity reactions
The purpose of this research is to review the available information about the classification and management of hypersensitivity reactions
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