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- Ribozyme - Wikipedia
These RNA catalysts may have pharmaceutical applications For example, a ribozyme has been designed to cleave the RNA of HIV If such a ribozyme were made by a cell, all incoming virus particles would have their RNA genome cleaved by the ribozyme, which would prevent infection
- 核酶_百度百科
核酶（ribozyme）是具有催化功能的小分子RNA，属于生物催化剂，通过切断RNA链的磷酸二酯键调控基因表达。 1982年，美国科学家T Cech在研究四膜虫rRNA前体时发现其内含子RNA具备自我剪接功能，该成果获1989年诺贝尔化学奖。
- Ribozyme-activated mRNA trans-ligation enables large gene delivery to . . .
Abstract Ribozymes are small catalytic RNA sequences capable of nucleotide-specific self-cleavage found widespread in nature Ribozyme cleavage generates distinct 2′,3′-phosphate and 5′-hydroxyl termini that resemble substrates for recently characterized RNA repair pathways in cells
- Ribozymes - Latest research and news | Nature
New structures of a methyltransferase ribozyme reveal the potential variety of RNA reactions and mechanisms
- 6. 7: Ribozymes - RNA Enzymes - Biology LibreTexts
Discuss the significance of ribozyme catalysis in the RNA world hypothesis and how modern ribozymes (and engineered artificial ribozymes) inform our understanding of early biocatalysis
- Ribocentre - Home
In addition to a brief introduction to ribozymes, on each ribozyme page, you’ll see a timeline of vital breakthroughs in ribozyme research, representative structures and the chemical mechanism of this ribozyme
- Ribozyme - an overview | ScienceDirect Topics
A ribozyme is an RNA molecule that can cleave phosphodiester bonds independently of protein-based enzymes It can be delivered in vivo as synthetic oligonucleotides or expressed from transgenes, with various chemical modifications tested to enhance stability, delivery, hybrid strength, and cleavage efficiency
- Ribocentre: a database of ribozymes - Oxford Academic
On the Ribozymes page, we list all the ribozyme families, showing the ribozyme name, a brief description, its year of discovery, and Rfam name and ID (Figure 1A)
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