- Is the full crossmatch valid after saline replacement
Hi all, We have a patient with strong rouleaux and an alloantibody According to our policy, we need to perform a full crossmatch which means the crossmatch is carried from immediate spin, to 37C and to AHG phases Due to the strong rouleaux, a saline replacement technique has to be used during t
- Do you wash your screening cells? For rouleaux? Why?
I had this patient with multiple myeloma Her antibody screen on gel card had rouleaux reactions for all 3 screening cells I then washed the screening cells six times with warm saline The screen was then negative Forgive me if this is dumb, but why wash the screen cells? Obviously it worked, b
- can you tell if Rouleaux is present just from looking at the gel card . . .
I apologize, this may be a stupid question For example, if you are trying to do a gel cross match and the donor cells have Rouleaux, can you tell that from looking at the gel card? If so, can you tell me where I can find some pictures of this reaction Thank you for your time and help in advance
- Rouleaux interference - Transfusion Services - PathLabTalk
Expand It's not uncommon to see rouleaux interference in Gel testing but it's not something we see frequently The crossmatch question is interesting: Technically, the screen is negative for alloantibody reactivity so I think you'd be able to follow your procedure for that result However, with the immediate spin crossmatch, you may have to perform a saline replacement to obtain a "compatible
- Rouleaux or cold auto - Transfusion Services - PathLabTalk
We perform our antibody screens at 37C and IAT only (since AABB STD's says methods that detect SIGNIFICANT antibodies) The problem is, that crossmatches are performed at Immediate Spin Cold autos are missed at antibody screening, and the screen is reported as negative When techs crossmatch units,
- Microscopes in the Blood Bank - PathLabTalk
Some time ago I posted a similar question on the AABB website and the consensus seemed to be that for the most part microscopes should be kept out of the blood bank Personally, having \"grown up\" with a microscope by my side through years in both transfusion services and reference laboratory, i
- Dealing With Cold Agglutinins - PathLabTalk
I suspected Rouleaux, and asked her to follow the saline replacement procedure, explaining that if it was true agglutination, saline replacement would not "correct" it
- anti-A1 or rouleaux? - Transfusion Services - PathLabTalk
Almost certainly because it is anti-A1, rather than rouleaux, or any other "cold" antibody specificity, such as anti-ALeb, but, come what may, unless the reactions are positive at STRICTLY 37oC, it wi
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