Pathogenesis of Listeria-Infected Drosophila wntD Mutants Is Associated . . . In this paper, we have identified genes that may mediate the susceptibility of wntD mutants to lethal infection These genes include eiger, a homolog of the mammalian TNF gene, and a previously uncharacterized gene called edin (elevated during infection)
p38 MAPK-Dependent Phagocytic Encapsulation Confers Infection Tolerance . . . Using a bacterial infection model in Drosophila, we uncovered a p38 MAP kinase-mediated mechanism of tolerance to intracellular bacterial infection as measured by the extent to which the host's survival rate increased or was maintained despite increasing bacterial burden
Systemic Bacterial Infection and Immune Defense Phenotypes in The procedure described here presents a methodological framework for delivering robust and repeatable bacterial infections to Drosophila melanogaster and subsequently measuring infection severity and quantifying the host immune response
Screening for genes affecting defense and endurance Three genome-wide RNA interference screens were performed in Drosophila S2 cells to dissect the contribution of host processes to Listeria monocytogenes entry, vacuolar escape, and