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- RASA2 a new gatekeeper for TCR signaling - Wiley Online Library
RASA2 is a RAS GTPase-activating protein (RasGAP), a family of proteins that are known to suppress RAS signaling pathways down-stream of T cell receptor (TCR) activation by conversion of RAS-GTP to RAS-GDP
- RASA2 a new gatekeeper for TCR signaling - Wiley Online Library
RASA2 is a RAS GTPase-activating protein (RasGAP), a family of proteins that are known to suppress RAS signaling pathways down-stream of T cell receptor (TCR) activation by conversion of RAS-GTP to RAS-GDP
- IBCH RAS, Russia Nizhny Novgorod State Medical Academy . . .
Diverse repertoires of hypervariable immunoglobulin receptors (TCR and BCR) recognize antigens in the adaptive immune system The development of immunoglobulin receptor repertoire sequencing methods makes it possible to perform repertoire-wide disease association studies of antigen receptor sequences We developed a statistical framework for associating receptors to disease from only a small
- The Ras MAPK Pathway Is Required for Generation of iNKT Cells
In this manuscript we present genetic evidence supporting a critical role of Ras, and its downstream effectors Egr-1, Egr-2 for positive selection of iNKT cells, suggesting that the signaling pathways emanating from the TCR during positive selection of conventional ab T cells and iNKT cells are similar
- ЗАКОН за развитието на академичния състав в Република България
3 "доцент"; 4 "професор" Чл 3 (1) (Изм - ДВ, бр 101 от 2010 г ) Процедурите за прием на редовни и задочни докторанти, както и за заемане на академични длъжности в акредитираните от Националната агенция за оценяване и
- Reedquist_TORJ
Abstract: Ras superfamily small GTPases represent a wide and diverse class of intracellular signaling proteins that are highly conserved during evolution These enzymes serve as key checkpoints in coupling antigen receptor, growth factor, cytokine and chemokine stimulation to cellular responses Once activated, via their ability to regulate multiple downstream signaling pathways, small GTPases
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