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- N a -Tosyl-Lys Chloromethyl Ketone, Hydrochloride
Inactivates trypsin irreversibly without affecting chymotrypsin Prevents nitric oxide production by activated macrophages by interfering with transcription of the iNOS gene Blocks cell-cell adhesion and binding of HIV-1 virus to target cells
- TLCK (Tosyl-L-lysyl-chloromethane hydrochloride), Trypsin . . . - Abcam
Irreversible inhibitor of trypsin and trypsin-like serine proteases Blocks LPS- or cytokine-induced NF-κB activation Inhibits caspase processing; blocks apoptosis Active in vitro and in vivo Soluble in water Stock solutions up to 10mM can be prepared in aqueous buffers with pH 6 0 or lower
- N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride (TLCK . . .
N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride (TLCK hydrochloride) is an irreversible inhibitor for serine protease, which inhibits trypsin and trypsin-like protease by alkylating histidine residues in their active site
- p-N- (7-Amino-1-chloro-2-oxohept-3-yl)toluenesulphonamide
Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C L Inventory Each notification may be associated with multiple companies Information may vary between notifications depending on impurities, additives, and other factors
- TLCK - Enzo
Chymotrypsin is not inhibited by TLCK, so this inhibitor can be used to block contaminating trypsin activity in chymoptrypsin preparations TLCK can be used in combination with a chymotrypsin inhibitor to prevent proteolytic degradation during the isolation of proteins
- Tosyllysine Chloromethyl Ketone (hydrochloride) (CAS 4272-74-6)
Tosyllysine chloromethylketone (TLCK) is an active site- directed agent that inhibits serine proteinases with trypsin- like activity
- TLCK | 4272-74-6 - ChemicalBook
Tosyllysine chloromethylketone (TLCK) is an active site-directed agent that inhibits serine proteinases with trypsin-like activity TLCK may also act non-selectively with thiol groups and thereby inhibit cysteine proteinases and other enzymes
- TLCK | Trypsin like protease inhibitor | Probechem Biochemicals
TLCK (Tos-Lys-CH2Cl, N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride ) is a specific, irreversible and covalent inhibitor of serine protease trypsin, modifies His-57 and Ser-195 of trypsin-like proteases and blocks the active site
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