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- TATES: Efficient Multivariate Genotype-Phenotype Analysis for . . . - PLOS
Multivariate genotype–phenotype methods do exist but attain maximal power only in special circumstances We present a new multivariate method called TATES (Trait-based Association Test that uses Extended Simes procedure)
- pgen. 1003235 1. . 9 - PLOS
Unlike other multivariate methods, TATES detects both genetic variants that are common to multiple phenotypes and genetic variants that are specific to a single phenotype, i e TATES provides a more complete view of the genetic architecture of complex traits
- Evaluation of the sugar-sweetened beverage tax in Oakland, United . . .
Justin White and co-workers report an evaluation of the 2017 sugar-sweetened beverage tax enacted in Oakland in California
- Understanding the influence of online misogyny in schools from the . . .
YouGov UK https: yougov co uk society articles 45735-how-many-britons-agree-andrew-tates-viewswomen#:~:text=Among%20Britons%20with%20a%20favourable,with%20his%20opinions%20regarding%20women
- A Comparison of Multivariate Genome-Wide Association Methods
We focused on six methods that are implemented in the software packages PLINK, SNPTEST, MultiPhen, BIMBAM, PCHAT and TATES, and also compared them to standard univariate GWAS, analysis of the first principal component of the traits, and meta-analysis of univariate results
- The transcription factor HLH-26 controls probiotic-mediated protection . . .
In the off state of the pathway, the β-catenin destruction complex facili-tates the phosphorylation of β-catenin by GSK3β, which induces ubiquitination of β-catenin and subsequent proteasomal degradation
- The global burden of perinatal depression: A call to action
The prevalence of perinatal depression is much greater in low-resource settings Globally, perinatal depression affects one in four women [5] with the greatest burden in lower-and-middle-income countries compared to high-income countries [6], largely due to the limited accessibility to mental health professionals and resources [7], as well as factors such as social stigma [8] and reduced
- Nuclear p62 SQSTM1 facilitates ubiquitin-independent proteasomal . . .
Structurally, p62 contains an N-terminal Phox and Bem1 (PB1) domain that facili-tates homotypic or heterotypic oligomerization of PB1 domain-containing proteins, a C-terminal ubiquitin association (UBA) domain that recognizes and binds to ubiquitin chains on ubiquitinated proteins, and a central microtubule-associated protein light chain 3 (LC3
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