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- Telomerase - Wikipedia
Telomerase, also called terminal transferase, [1] is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres A telomere is a region of repetitive sequences at each end of the chromosomes of most eukaryotes
- Telomerase | Description, Function, Facts | Britannica
Telomerase is an enzyme that influences cell life span by adding organic compounds known as nucleotides to telomeres, segments of DNA located at the ends of chromosomes
- Telomerase - an overview | ScienceDirect Topics
Telomerase is a reverse transcriptase that adds repeats of a DNA sequence (TTAGGG) to the ends of chromosomes (telomeres) in mitotic cells, thus maintaining their length and preventing cell cycle arrest and cell death (cellular senescence)
- Telomeres and Telomerase: Structure and Functions - Microbe Notes
In eukaryotes, telomerase, a telomeric enzyme includes a catalytic protein subunit known as telomerase reverse transcriptase (hTERT) and a core RNA component (hTR) that synthesizes and maintains the telomere structure with uncontrolled cell growth and is linked to the development of cancer
- Telomeres and telomerase (article) | Khan Academy
Some cells have the ability to reverse telomere shortening by expressing telomerase, an enzyme that extends the telomeres of chromosomes Telomerase is an RNA-dependent DNA polymerase, meaning an enzyme that can make DNA using RNA as a template
- The role of telomere and telomerase in cancer and novel therapeutic . . .
Telomeres are dynamic complexes at the ends of chromosomes that are made up of protective proteins and tandem repeating DNA sequences In the large majority of cancer cells, telomere length is maintained by telomerase, an enzyme that elongates telomeres
- What Is Telomerase Activity and Why Is It Important?
Telomerase is the enzyme that counteracts this shortening by adding new telomeric DNA sequences, thereby maintaining or extending telomere length Telomerase is classified as a ribonucleoprotein reverse transcriptase enzyme
- PDB-101: Molecule of the Month: Telomerase
The telomerase enzyme is a specialized reverse transcriptase (TERT) that uses this RNA template to create the telomere DNA A collection of other proteins assist with the process, bringing telomerase to the telomere when it’s needed, and holding the telomere DNA end so that many repeats can be added in succession
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