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High grade prostatic intraepithelial neoplasia (HGPIN) Cancers associated with HGPIN diagnosis on initial biopsy are more likely to be low grade and organ confined as compared to cancers diagnosed in the first biopsy without preexisting HGPIN (Can J Urol 2015;22:8056, Am J Surg Pathol 2011;35:1165)
Diagnosis, Management, And Follow-Up Strategies For High . . . - Propath By Bahram Robert Oliai, M D In my pathology practice one issue that seems to come up frequently as a cause of frustration to both my urologist colleagues, and perhaps more so to their patients, is what to do following a diagnosis of high grade prostatic intraepithelial neoplasia (HGPIN) and or so-called atypical acini, the now infamous “atypical small acinar proliferation,” (A K A ASAP
High-grade prostatic intraepithelial neoplasia - Wikipedia High-grade prostatic intraepithelial neoplasia (HGPIN) is an abnormality of prostatic glands and believed to precede the development of prostate adenocarcinoma (the most common form of prostate cancer) [1][2] It may be referred to simply as prostatic intraepithelial neoplasia (PIN) It is considered to be a pre-malignancy, or carcinoma in situ, of the prostatic glands
What Is High-Grade Prostatic Intraepithelial Neoplasia? High-grade prostatic intraepithelial neoplasia does not cause noticeable symptoms and is usually discovered incidentally when a prostate biopsy is performed for other reasons Common indications for a prostate biopsy include an elevated prostate-specific antigen (PSA) blood test result or an abnormal finding during a digital rectal exam (DRE)
High-Grade Prostatic Intraepithelial Neoplasia - PMC High-grade prostatic intraepithelial neoplasia is considered the most likely precursor of prostatic carcinoma The only method of detection is biopsy; prostatic intraepithelial neoplasia (PIN) does not significantly elevate serum prostate-specific
FAQS: HIGH GRADE PROSTATIC INTRAEPITHELIAL NEOPLASIA In most cases a repeat biopsy done soon after the diagnosis of high grade prostatic intraepithelial neoplasia is not useful as the chance of finding cancer is low
HGPIN - Inform Diagnostics HGPIN on its own does not cause When PIN is diagnosed by a symptoms It also does not elevate pathologist, it will be classified either PSA Usually it is diagnosed when a as low-grade or high-grade, depending man has a biopsy to look into another on the level of changes seen in the prostate problem, such as an enlarged cells This is an important distinction prostate, that has caused
Precancerous Lesions of the Prostate: Overview, PIN and ASAP Rates . . . Prostatic intraepithelial neoplasia (PIN), particularly high-grade PIN (HGPIN), and atypical small acinar proliferation (ASAP) have been identified as precancerous lesions of the prostate; that is, precursor lesions to prostatic carcinoma PIN refers to the precancerous end of a morphologic spectrum involving cellular proliferation within pro