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ACAN mutations as a cause of familial short stature - PMC Aggrecan, encoded by ACAN, is a major proteoglycan component of the extracellular matrix in the growth plate and articular cartilage Aggrecan provides the hydrated gel structure important for the load-bearing properties of joints and plays a key role in cartilage and bone morphogenesis
Aggrecan - Wikipedia Aggrecan (ACAN), also known as cartilage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1, is a protein that in humans is encoded by the ACAN gene [5]
ACAN! Architects Climate Action Network UK ACAN is a network of individuals and organisations within architecture and related built environment professions taking action to address the twin crises of climate and ecological breakdown
ACAN gene: MedlinePlus Genetics The ACAN gene provides instructions for making the aggrecan protein Learn about this gene and related health conditions
Acute Care Action Network (ACAN) The WHO Acute Care Action Network (ACAN) is a global alliance of key stakeholders committed to saving millions of lives by advancing acute care through collaboration
ACAN | Test catalog | Invitae Diagnostic testing of this gene is recommended to identify a potential genetic basis for a condition This type of testing can inform prognosis and clinical care for a symptomatic patient or be used to screen unaffected patients (including family members) for increased genetic risk for the condition
ACAN Gene: Function, Mutations, and Related Conditions The ACAN gene provides the instructions for a protein essential for the body’s skeletal framework, directing a core component for the healthy development of cartilage and bone Its role is prominent during early development when the skeleton is first forming
Orphanet: ACAN-aggrecan Orphanet is part of the Gene Curation Coalition, a global effort to harmonise gene-level resources