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Tocilizumab (Actemra®) - Johns Hopkins Arthritis Center What is Tocilizumab (Actemra®)? Tocilizumab is in a class of drugs called biologics Tocilizumab is a treatment for adults with moderate to severe rheumatoid arthritis (RA), giant cell arteritis, and polyarticular and systemic juvenile idiopathic arthritis You must have tried and failed another medication for RA before starting tocilizumab Tocilizumab blocks a substance called IL-6, known