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Pax genes - Wikipedia Groups Within the mammalian family, there are four well defined groups of Pax genes Pax group 1 (Pax 1 and 9), Pax group 2 (Pax 2, 5 and 8), Pax group 3 (Pax 3 and 7) and Pax group 4 (Pax 4 and 6)
Overview of PAX gene family: analysis of human tissue-specific variant . . . Paired-box (PAX) genes encode a family of highly conserved transcription factors found in vertebrates and invertebrates PAX proteins are defined by the presence of a paired domain that is evolutionarily conserved across phylogenies
The PAX Genes: Roles in Development, Cancer, and Other Diseases - MDPI Humans possess a group of nine related genes that form the PAX gene family These genes encode proteins known as the PAX transcription factors, which control gene expression on a large scale and coordinate the development of bodily structures such as the eyes and muscles
Pax Genes - an overview | ScienceDirect Topics Pax genes refer to a family of nine homologous genes crucial for mammalian development, characterized by a paired domain that binds to DNA, and are involved in the formation of sense organs, the nervous system, and cellular differentiation during epithelial-mesenchymal transitions
The PAX Genes: Roles in Development, Cancer, and Other Diseases Humans possess a group of nine related genes that form the PAX gene family These genes encode proteins known as the PAX transcription factors, which control gene expression on a large scale and coordinate the development of bodily structures such as the eyes and muscles
Pax genes in embryogenesis and oncogenesis - PMC The paired box genes are a family of nine developmental control genes, which in human beings (PAX) and mice (Pax) encode nuclear transcription factors The temporal and spatial expressions of these highly conserved genes are tightly regulated during foetal development including organogenesis
Origins and evolvability of the PAX family - ScienceDirect This review highlights some important aspects of the molecular evolution of the PAX -like genes, and provides discussion of their putative adaptive implications Additionally, we mined the available genomic proteomic databases for new data relevant to the topics discussed here
The Pax gene family: Highlights from cephalopods - PLOS Introduction Pax proteins belong to a family of transcription factors playing important roles in development of metazoans, from early specification of cell fate to body patterning through morphogenesis of various tissues and organs [1,2]