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Stochastic gates for covariate selection in population pharmacokinetics . . . Covariate selection in population pharmacokinetics modelling is essential for understanding interindividual variability in drug response and optimizing dosing Traditional stepwise covariate modelling is often time-consuming, compared to the new machine learning alternatives
Application of machine learning techniques in population . . . Machine learning has demonstrated excellent capabilities for prescreening covariates and developing predictive models This review introduces various applications of machine learning techniques in pop-PK PD research
Population Pharmacokinetics PD Modelling: a Systematic Review individual changes in anatomical and physiological variables Population modeling requires a strong foundation of processes to ensure accurate data, appropriate computational platforms, ufficient resources, and good communication are all required This paper examines the various meth