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The use of unnatural amino acids to study and engineer . . . The expansion of the genetic code for the incorporation of unnatural amino acids (UAAs) in proteins of bacteria, yeasts, mammalian cells or whole animals provides molecular and structural biologists with an amazing kit of novel tools
Proteins Carrying One or More Unnatural Amino Acids Different strategies for global and site-specific incorporation of amino acid analogues into proteins both in vitro and in vivo have been developed allowing a wide range of potential applications of unnatural amino acid mutagenesis
Probing Ion Channel Structure and Function Using Light . . . Approaches to remotely control and monitor ion channel operation with light are expanding rapidly in the biophysics and neuroscience fields A recent development directly introduces light sensitivity into proteins by utilizing photosensitive unnatural amino acids (UAAs) incorporated using the genetic code expansion technique
Unnatural Amino Acids for Biological Spectroscopy and . . . Due to advances in methods for site-specific incorporation of unnatural amino acids (UAAs) into proteins, a large number of UAAs with tailored chemical and or physical properties have been developed and used in a wide array of biological applications