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JAK2 Gene Mutation: Causes and Related Conditions The Janus kinase 2 (JAK2) gene directs cells to make the JAK2 protein, which stimulates cell growth and division Learn what can cause a JAK2 gene mutation and associated conditions
What Is Life Expectancy With a JAK2 Mutation? - Biology Insights Life expectancy for individuals with a JAK2 mutation varies considerably It largely depends on the specific myeloproliferative neoplasm (MPN) diagnosed, the patient’s age at diagnosis, their overall health, and other risk factors
Polycythemia vera: 2024 update on diagnosis, risk-stratification, and . . . Risk factors for survival include older age, leukocytosis, abnormal karyotype, and the presence of adverse mutations Twenty-year risk for thrombosis, post-PV MF, or AML are 26%, 16% and 4%, respectively or thrombosis history) and low (absence of both risk factors) Additional predictors
JAK2 Mutation Can Lead to Essential Thrombocythemia Diagnosis Essential thrombocythemia (ET) is a rare disease People who have it, though, on average, tend to have a normal life expectancy People who have ET have an increased number of platelets Platelets are the smallest of the blood cells and help your blood to clot