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Management of moderate and severe alcohol withdrawal syndromes The ambulatory management of mild alcohol withdrawal, the initial diagnosis and treatment of alcohol use disorder, and specific conditions due to alcohol-related organ damage (eg, cirrhosis, pancreatitis) are discussed separately
Wernicke encephalopathy - UpToDate Wernicke-Korsakoff syndrome is the best known neurologic complication of thiamine (vitamin B1) deficiency [1] The term refers to two different syndromes, each representing a different stage of the disease
Overview of the chronic neurologic complications of alcohol Alcohol dependence is also a chronic disease, associated with malnutrition, trauma, and a wide variety of central nervous system disorders [1] Wernicke-Korsakoff syndrome is the best known neurologic complication of thiamine (vitamin B1) deficiency [2]
Alcohol use disorder: Pharmacologic management - UpToDate Initiating pharmacologic management in individuals hospitalized for alcohol-related disorders (eg, alcohol-related gastritis, alcohol-related cardiomyopathy, pancreatitis, liver disease) appears to reduce alcohol use and improve clinical outcomes
Alcohol withdrawal: Ambulatory management - UpToDate Ambulatory management of alcohol withdrawal is reviewed here Individuals with more severe symptoms of withdrawal, or at risk for developing severe symptoms such as delirium or seizures require closer monitoring, typically in an inpatient setting
Causes of lactic acidosis - UpToDate Explore the pathophysiology and causes of lactic acidosis, including impaired oxygenation and its effects on lactate production
Moderate and severe alcohol withdrawal: Rapid overview Moderate and severe alcohol withdrawal: Rapid overview CSF: cerebrospinal fluid; CT: computed tomography; IV: intravenous * The thiamine dose range provided is for the prevention of Wernicke encephalopathy (WE) Treatment of diagnosed WE requires higher doses Refer to UpToDate topic discussing WE for details
Management of moderate and severe alcohol withdrawal syndromes The ambulatory management of mild alcohol withdrawal, the initial diagnosis and treatment of alcohol use disorder, and specific conditions due to alcohol-related organ damage (eg, cirrhosis, pancreatitis) are discussed separately
Acute toxic-metabolic encephalopathy in adults - UpToDate Certain metabolic encephalopathies, including those caused by sustained hypoglycemia and thiamine deficiency (Wernicke encephalopathy), may result in permanent structural brain damage if untreated
Nutrition status in patients with sustained heavy alcohol use This topic addresses the epidemiology, pathogenesis, assessment, and treatment of malnutrition in individuals with sustained heavy alcohol use Malnutrition in patients with chronic liver disease is discussed separately: