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Breast Cancer HER2 Status | What is HER2 Status? Breast Cancer HER2 Status About 15% to 20% of breast tumors have higher levels of a protein known as HER2 These cancers are called HER2-positive breast cancers Ask your cancer care team about your HER2 status and what it means for you
HER2-positive breast cancer: What is it? - Mayo Clinic HER2-positive breast cancer is a breast cancer that tests positive for a protein called human epidermal growth factor receptor 2 (HER2) This protein promotes the growth of cancer cells In about 1 of every 5 breast cancers, the cancer cells have extra copies of the gene that makes the HER2 protein
HER2 positive breast cancer: What it is, diagnosis and . . . What are the treatment options for HER2 positive breast cancer? Treatment for HER2 positive breast cancer depends on the tumor’s size Patients with tumors smaller than 2 centimeters, with no lymph nodes affected, will undergo surgery first, followed by chemotherapy and a single antibody targeting the HER2 protein known as trastuzumab
HER2-positive breast cancer - Penn Medicine HER2-positive breast cancer does not present itself through any unique symptoms Common signs of this breast cancer type align with the typical breast cancer symptoms and may be detected by a mammogram at routine breast cancer screening: Changes in breast shape Mass or suspicious finding on a mammogram Breast lump Breast or nipple pain Discharge from the nipple Nipple inversion Swelling of the
Breast Cancer Stages | Understanding Breast Cancer Staging If the breast cancer cells have more than the normal amount of HER2 receptors on their surface, the cancer cells are called HER2 positive (HER2+) If the breast cancer cells have a normal amount of HER2 on their surface, the cancer cells are called HER2 negative (HER2-)
HER2 Status and HER2-Positive Breast Cancer The HER2 (human epidermal growth factor receptor 2) gene makes HER2 proteins (also called HER2 neu proteins) HER2 proteins are receptors on breast cells HER2 receptors help control how a breast cell grows, divides, and repairs itself
Treatment options for HER2-positive breast cancer Treatment for HER2-positive breast cancer depends on tumor size and spread but may involve a combination of chemotherapy, targeted therapy, monoclonal antibody therapy, and kinase inhibitors
HER2-positive or HER2-low breast cancer - LBBC HER2-positive or HER2-low breast cancer is caused by a genetic mutation in the HER2 gene Learn more about the causes and treatment options for HER2-positive breast cancer