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Science | AAAS Science AAAS peer-reviewed journals deliver impactful research, daily news, expert commentary, and career resources
Targeted MYC2 stabilization confers citrus Huanglongbing . . . DOI: 10 1126 science adq7203 Editor’s summary Abstract PUB21 is an S gene for citrus HLB A PUB21 dominant-negative paralog from Citrus relatives confers HLB resistance MYC2 is a proteolytic substrate of PUB21 The PUB21-MYC2 module activates jasmonate-mediated defense Helitron transposition generates a regulatory circuit between PUB21 and MYC2
Tellurium nanowire retinal nanoprosthesis improves vision in . . . Present vision restoration technologies have substantial constraints that limit their application in the clinical setting In this work, we fabricated a subretinal nanoprosthesis using tellurium nanowire networks (TeNWNs) that converts light of both the
Science Journal - AAAS Science is the leading multidisciplinary, international journal of peer-reviewed research including analysis and news coverage of breakthroughs and policy
Deep learning–guided design of dynamic proteins | Science Deep learning has advanced the design of static protein structures, but the controlled conformational changes that are hallmarks of natural signaling proteins have remained inaccessible to de novo design Here, we describe a general deep learning–guided
Identification of proliferating neural progenitors in the adult . . . Whether adult neurogenesis occurs in the human hippocampus is one of the most debated issues in neuroscience Dumitru et al used a single-cell transcriptomic approach to address this issue in human samples of various ages from birth through adulthood (see the Perspective by Quiniou and Jessberger) Machine learning algorithms helped the authors to identify proliferating neural progenitor
Spontaneous formation of robust two-dimensional perovskite . . . The two-dimensional on three-dimensional (2D 3D) perovskite bilayer heterostructure can improve the stability and performance of perovskite solar cells We show that the 2D 3D perovskite stack in a device evolves dynamically during its end-of-life
Is the dire wolf back from the dead? Not exactly - Science The company’s chief science officer Beth Shapiro, an evolutionary biologist who co-authored the 2021 Nature study, tells New Scientist that her team sequenced the complete genome of the dire wolf from newly analyzed ancient DNA from fossils on its way toward engineering Romulus, Remus, and Khaleesi