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Hemophagocytic Lymphohistiocytosis: Symptoms, Causes Outlook Hemophagocytic lymphohistiocytosis (HLH) is a condition that occurs when your immune system abnormally overreacts Your immune system defends your body from things that make you sick, like bacteria and viruses Cells, proteins, organs and tissues work together to keep you healthy
Hemophagocytic Lymphohistiocystosis - Johns Hopkins Medicine In adults, many different conditions, including infections and cancer, can cause HLH If you have HLH, your body's defense system, called your immune system, does not work normally Certain white blood cells — histiocytes and lymphocytes — attack your other blood cells
Hemophagocytic lymphohistiocytosis (HLH) | Immune Deficiency Foundation Hemophagocytic lymphohistiocytosis (HLH) is a severe, systemic inflammatory syndrome that can be fatal This syndrome can sometimes occur in people with medical problems that cause a strong activation of the immune system, such as an infection or cancer
Hemophagocytic Lymphohistiocytosis (HLH) | Childrens Hospital of . . . Hemophagocytic lymphohistiocytosis (HLH) is rare life-threatening syndrome that can affect infants, children, adolescents and adults HLH is not a single disease, however; it is a group of disorders of the immune system that can be triggered by infections, cancer or rheumatologic diseases
Hemophagocytic lymphohistiocytosis: A disorder of T cell activation . . . Hemophagocytic lymphohistiocytosis (HLH) is a disorder that has been recognized since the middle of the last century In recent decades, increasing understanding of the genetic roots and pathophysiology of HLH has led to improved diagnosis and treatment of this once universally fatal disorder
Hemophagocytic lymphohistiocytosis: do we have a solution for TMI (too . . . Hemophagocytic lymphohistiocytosis (HLH) and the related HLH-spectrum disorders macrophage activation syndrome, macrophage activation-like syndrome, and treatment-associated immune-effector-cell–associated HLH-like syndrome are extreme forms of too much inflammation (TMI) Adult patients with HLH associated with hematologic malignancies have a 70% to 80% mortality rate due to delayed