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Celiac disease - Symptoms and causes - Mayo Clinic Celiac disease is an autoimmune condition where the immune system reacts to gluten, sometimes causing damage to the small intestine Gluten is a protein found in foods containing wheat, barley or rye If you have celiac disease, eating gluten triggers an immune response to the gluten protein in your small intestine Over time, this reaction can damage your small intestine's lining and prevent
Celiac disease - Diagnosis and treatment - Mayo Clinic Many people with celiac disease don't know they have it Two blood tests can help diagnose it: Serology testing looks for antibodies in your blood Elevated levels of certain antibody proteins indicate an immune reaction to gluten Genetic testing for human leukocyte antigens (HLA-DQ2 and HLA-DQ8