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Understanding risks with intrathecal administration – SPS . . . All NHS Trusts that provide an intrathecal chemotherapy service must comply with the national guidance on the safe administration of intrathecal chemotherapy (archived by the Department of Health) to protect patients The SPS article on managing an intrathecal chemotherapy service provides more information
Mitigate Risks with Intrathecal Chemotherapy Medications compounded for intrathecal administration require specific safety steps during the preparation process due to the high-risk site of administration Intrathecal administration is characterized as an injection into the cerebrospinal fluid (CSF) in the lumbar sac via a needle directly into the intraspinal space, or as an injection through an Ommaya reservoir that allows the medication
Safety, Pharmacokinetic and Clinical Activity of Intrathecal . . . Intrathecal pemetrexed at a dose of 30 mg via Ommaya reservoirs on Days 1 and 8 every 21 days achieved promising disease control and satisfactory survival with moderate toxicities in resistant LUAD-LM, providing a feasible and effective option, especially for the patients who cannot tolerate LP
The Safe Administration of Intrathecal Chemotherapy Clinical . . . 2 5 2 The Prescription 2 5 2 1 The purpose designed intrathecal chemotherapy chart must always be used for prescribing, dispensing and administering intrathecal chemotherapy Where a regimen is prescribed using a computerised chemotherapy prescribing system e g Aria, and intrathecal chemotherapy is part of that regimen, it is acceptable to include the intrathecal dose on the main
Intrathecal Chemotherapy (IT Chemo) - OncoLink Intrathecal chemotherapy can be given during a lumbar puncture or through an ommaya reservoir (shunt) Before having IT chemotherapy, you will have lab work done to check your blood counts
Intrathecal Chemotherapy Your doctor has prescribed intrathecal chemotherapy (which is cytotoxic or cell toxic treatment) for your condition This means that you will have chemotherapy drugs given by injection into the fluid around the spinal cord by a lumbar puncture procedure